SCHEMBL28607196

SCHEMBL28607196

Clc1ccc2c(c1)-c1cc(Cl)ccc1-c1ccc(Cl)cc1-c1cc(Cl)ccc1-2

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.68
PPOX P50336 1/20 0.52
TP53 P04637 2/20 0.47
CYP2A6 P11509 2/20 0.47
LMNA P02545 1/20 0.47
AHR P35869 2/20 0.46
TSHR P16473 5/20 0.43
CYP3A4 P08684 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALOX15 P16050 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSP90AA1 P07900 1/20 0.43
GPR3 P46089 1/20 0.42
HSD17B10 Q99714 2/20 0.41
CES1 P23141 2/20 0.41
PDK2 Q15119 1/20 0.41
TGM2 P21980 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7799443 0.91 S100A4 (0.70) S100A4PPOXTP53CYP2A6LMNA
SCHEMBL12887899 0.91 S100A4 (0.70) S100A4PPOXTP53CYP2A6LMNA
SCHEMBL29581505 0.82 S100A4 (0.71) S100A4PPOXHSP90AA1CES1TGM2
SCHEMBL1133148 0.82 S100A4 (0.90) S100A4PPOXHSP90AA1CES1TGM2
SCHEMBL11876117 0.82 S100A4 (0.80) S100A4PPOXLMNASMN1; SMN2HSP90AA1
SCHEMBL10924194 0.82 S100A4 (0.50) S100A4PPOXTP53CYP2A6LMNA
SCHEMBL30345128 0.82 S100A4 (0.90) S100A4PPOXHSP90AA1CES1TGM2
SCHEMBL4319897 0.82 S100A4 (0.71) S100A4PPOXHSP90AA1CES1TGM2
SCHEMBL2599342 0.82 S100A4 (1.00) S100A4PPOXLMNAALDH1A1SMN1; SMN2
SCHEMBL31677417 0.80 S100A4 (0.57) S100A4TP53CYP2A6LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113087726-A Arylamine organic semiconductor material and application thereof in photoelectric device 浙江大学 2021-07-09 CN disclosed