Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369235 | 0.81 | AAK1 (0.38) | CREBBPAAK1 | |
| SCHEMBL25411497 | 0.79 | AKR1C3 (0.31) | AKR1C3AKR1C2 | |
| SCHEMBL4235241 | 0.70 | AKR1C3 (0.35) | AKR1C3AKR1C2AKR1C1PTGS1GAA | |
| SCHEMBL24328838 | 0.70 | IMPDH2 (0.32) | AAK1 | |
| SCHEMBL24328853 | 0.70 | IMPDH2 (0.32) | AAK1 | |
| Hydrochloric Acid SCHEMBL4231451 | 0.69 | AKR1C3 (0.35) | AKR1C3AKR1C2AKR1C1PTGS1GAA | |
| SCHEMBL22411540 | 0.69 | CTSK (0.36) | AKR1C3AKR1C2AKR1C1PTGS1KDM4E | |
| SCHEMBL25412521 | 0.68 | AAK1 (0.36) | AAK1 | |
| SCHEMBL8995856 | 0.68 | KMT2A (0.55) | HTTSMN1; SMN2KDM4E | |
| SCHEMBL6274860 | 0.67 | CYP3A4 (0.44) | AKR1C3AKR1C2AKR1C1PTGS1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565258-A2 | COMPOSITIONS FOR THE TREATMENT OF DISEASE | Sightstream Biotherapeutics, Inc. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030950-A2 | COMPOSITIONS FOR THE TREATMENT OF DISEASE | SIGHTSTREAM BIOTHERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |
| WO-2022177635-A2 | COMPOSITIONS AND METHODS FOR MICROBIAL DISEASE TREATMENT | RA PHARMACEUTICALS, INC. (US) | 2022-08-25 | — | — | WO | disclosed |
| CN-113226368-A | Neurological disease treatment with zilucoprol | RA制药公司 | 2021-08-06 | — | — | CN | disclosed |