Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24220807 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL22011478 | 0.89 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28604432 | 0.88 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL24220741 | 0.87 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28597530 | 0.86 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28597529 | 0.86 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL24220733 | 0.86 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28594993 | 0.86 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL22010658 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28604431 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227091-A | As AM2Heterocyclic spiro-compounds as receptor inhibitors | 谢菲尔德大学 | 2021-08-06 | — | — | CN | disclosed |