Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL3953242 | 0.98 | PTK2 (0.44) | PTK2HRH4LMNAHTTSMN1; SMN2 | |
| SCHEMBL4759953 | 0.78 | PIK3CD (0.55) | — | |
| SCHEMBL6001202 | 0.75 | ACP1 (0.54) | LMNAHTTKDM4EALDH1A1TSHR | |
| SCHEMBL14259395 | 0.73 | TERT (0.47) | LMNAHTTSMN1; SMN2CDC7CDK2 | |
| SCHEMBL16344606 | 0.72 | CYP3A4 (0.45) | LMNACDC7CDK2ROCK1BIRC5 | |
| SCHEMBL27322596 | 0.70 | CDC7 (0.56) | CDC7CDK2ROCK1BIRC5PRKD3 | |
| SCHEMBL14159961 | 0.70 | HIF1A (0.57) | LMNASMN1; SMN2ADORA2AALDH1A1TSHR | |
| SCHEMBL28920361 | 0.70 | CYP1A2 (0.58) | LMNASMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL28606942 | 0.70 | BIRC5 (0.50) | LMNABIRC5 | |
| SCHEMBL28612598 | 0.70 | CYP1A2 (0.51) | LMNAHTTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096254-B | Quinazoline derivative and preparation method and application thereof | 江西师范大学 | 2021-07-06 | — | — | CN | disclosed |