Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124911 | 0.84 | TERT (0.44) | TERTBIRC5PRKD3PRKCGPRKCB | |
| SCHEMBL5715911 | 0.75 | BIRC5 (0.48) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL27677960 | 0.74 | HTT (0.61) | ROCK1KDM4EALDH1A1POLBTP53 | |
| SCHEMBL6001202 | 0.74 | ACP1 (0.54) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL22648975 | 0.74 | ALDH1A1 (0.56) | TERTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5802505 | 0.73 | KDM4E (0.54) | TERTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28607284 | 0.73 | PTK2 (0.45) | TERTBIRC5PRKD3PRKCGPRKCB | |
| SCHEMBL13483670 | 0.72 | BIRC5 (0.50) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL14159961 | 0.72 | HIF1A (0.57) | ALDH1A1HSD17B10SMN1; SMN2TDP1POLB | |
| SCHEMBL13483674 | 0.72 | BIRC5 (0.46) | BIRC5PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064878-A1 | Low cost, high yield, industrial scale reaction of 4-halopyridine and indole derivatives in presence of strong organic base; heavy metal catalyst free | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080064878-A1 | Low cost, high yield, industrial scale reaction of 4-halopyridine and indole derivatives in presence of strong organic base; heavy metal catalyst free | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064878-A1 | Low cost, high yield, industrial scale reaction of 4-halopyridine and indole derivatives in presence of strong organic base; heavy metal catalyst free | IDO1, IDO2, TDO2 | TERT 3608/4885BIRC5 2225/4885PRKD3 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.