SCHEMBL2860760

SCHEMBL2860760

CCCCN(N)[C@@H](CCCCN)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.43
RNPEP Q9H4A4 1/20 0.42
CPB2 Q96IY4 4/20 0.41
GRIK1 P39086 2/20 0.40
GRIK2 Q13002 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40
GNAI3 P08754 1/20 0.39
GNAO1 P09471 1/20 0.39
GNAI1 P63096 1/20 0.39
SLC6A5 Q9Y345 1/20 0.38
GPR84 Q9NQS5 3/20 0.38
FFAR1 O14842 1/20 0.38
SLC1A3 P43003 1/20 0.38
MAPT P10636 1/20 0.37
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
DPP8 Q6V1X1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11308884 0.95 GRIK1 (0.42) GSRRNPEPCPB2GRIK1GRIK2
SCHEMBL11305652 0.90 GRIK1 (0.40) GSRCPB2GRIK1GRIK2SLC1A2
Lysine SCHEMBL28835819 0.88 GSR (0.56) GSRGRIK1GRIK2SLC1A2SLC1A1
SCHEMBL6267879 0.84 GSR (0.47) GSRRNPEPCPB2GRIK1GRIK2
SCHEMBL26912122 0.83 GSR (0.43) GSRRNPEPCPB2GRIK1GRIK2
SCHEMBL6860131 0.83 GRIK1 (0.49) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL30037850 0.81 FOLH1 (0.49) GSRRNPEPCPB2GRIK1GRIK2
SCHEMBL14228039 0.80 GSR (0.50) GSRRNPEPCPB2
SCHEMBL9634474 0.80 NOD1 (0.49) GSRRNPEPCPB2GRIK1GRIK2
SCHEMBL9634471 0.80 NOD1 (0.49) GSRRNPEPCPB2GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820146-B2 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2010-10-26 US disclosed
EP-1515684-B1 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM OREAL (FR) 2010-05-19 EP disclosed
US-20050245673-A1 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2005-11-03 US disclosed