Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308884 | 0.95 | GRIK1 (0.42) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL2860760 | 0.90 | GSR (0.43) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| Lysine SCHEMBL28835819 | 0.88 | GSR (0.56) | GRIK1GRIK2SLC1A2SLC1A1NOD1 | |
| SCHEMBL8019482 | 0.83 | AKR1B1 (0.44) | GPR84FFAR1NOD1PPARD | |
| SCHEMBL9289262 | 0.83 | NOD1 (0.40) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL472903 | 0.83 | NOD1 (0.40) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL6860131 | 0.83 | GRIK1 (0.49) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL5495880 | 0.82 | NOD1 (0.42) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL5495885 | 0.82 | NOD1 (0.42) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL28182375 | 0.81 | GRIK1 (0.40) | GRIK1GRIK2SLC1A2SLC1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012194-B1 | PROCESS FOR THE PREPARATION OF N-CARBOXYALKYL-1-AMINOALKANE DIPHOSPHONIC ACIDS AND CARBOXYALKYLAMINO-PHENYL-METHANE DIPHOSPHONIC ACIDS | Benckiser-Knapsack GmbH (DE) | 1982-02-03 | — | — | EP | claimed |