Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282173 | 0.87 | LMNA (0.49) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL1160497 | 0.85 | LMNA (0.55) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5065716 | 0.84 | LMNA (0.47) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL28618725 | 0.81 | GAA (0.53) | LMNAALDH1A1KDM4EMAPTGLA | |
| SCHEMBL9923064 | 0.81 | LMNA (0.45) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL10503868 | 0.80 | HSD17B10 (0.46) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL10288757 | 0.80 | LMNA (0.44) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL10504114 | 0.80 | CYP4F2 (0.47) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL402047 | 0.79 | LMNA (0.51) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL9149975 | 0.79 | HIF1A (0.49) | LMNAALDH1A1KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299270-B | Preparation method of disubstituted pyrrole compound | 中国科学院宁波材料技术与工程研究所 | 2021-08-17 | — | — | CN | disclosed |