Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282173 | 0.86 | LMNA (0.49) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL28607697 | 0.84 | LMNA (0.48) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL1160497 | 0.83 | LMNA (0.55) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL9923064 | 0.80 | LMNA (0.45) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL10504114 | 0.79 | CYP4F2 (0.47) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL10503868 | 0.79 | HSD17B10 (0.46) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL10288757 | 0.79 | LMNA (0.44) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL2361219 | 0.79 | LMNA (0.50) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL402047 | 0.78 | LMNA (0.51) | LMNAALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL9149975 | 0.78 | HIF1A (0.49) | LMNAALDH1A1KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234132-A1 | Microcin B17 Analogs And Methods For Their Preparation And Use | PLANT BIOSCIENCE LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234132-A1 | Microcin B17 Analogs And Methods For Their Preparation And Use | MCM3, MCM7, CCNB3 | LMNA 478/4885ALDH1A1 4423/4885KDM4E 4277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.