Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | KRAS | P01116 | 6/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 6/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | WHR1 | P49842 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605668 | 1.00 | PDE4A (0.53) | PDE4APDE4DPDE3BPDE3AKRAS | |
| SCHEMBL28605978 | 0.81 | SMN1; SMN2 (0.52) | PDE3BPDE3AEGFRKDM4EACHE | |
| SCHEMBL13335780 | 0.79 | PDE4A (0.57) | PDE4APDE4DPDE3BPDE3AKRAS | |
| SCHEMBL27866064 | 0.79 | PDE4A (0.50) | PDE4APDE4DPDE3BPDE3AKRAS | |
| SCHEMBL8140684 | 0.78 | PDE4A (0.55) | PDE4APDE4DPDE3BPDE3AKRAS | |
| SCHEMBL13899607 | 0.78 | PDE4A (0.55) | PDE4APDE4DPDE3BPDE3AKRAS | |
| SCHEMBL26069352 | 0.77 | KRAS (0.58) | PDE4APDE4DPDE3BPDE3AKRAS | |
| SCHEMBL29723105 | 0.76 | PDE4A (0.54) | PDE4APDE4DPDE3BPDE3AKRAS | |
| SCHEMBL20813455 | 0.76 | PDE4A (0.54) | PDE4APDE4DPDE3BPDE3AKRAS | |
| SCHEMBL372259 | 0.76 | PDE4A (0.54) | PDE4APDE4DPDE3BPDE3AKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004210-A | Quinazoline-4-selenium salt compound, preparation method and biological activity | 鲁东大学 | 2021-06-22 | — | — | CN | disclosed |