Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 10/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503120 | 0.92 | P2RX7 (0.47) | P2RX7NPC1RAB9ACNR2TAS1R3 | |
| SCHEMBL13162628 | 0.89 | NPC1 (0.51) | P2RX7NPC1RAB9ACNR2CNR1 | |
| SCHEMBL28602013 | 0.84 | CHRM1 (0.60) | HTR4 | |
| SCHEMBL13161996 | 0.81 | NAMPT (0.50) | P2RX7NPC1RAB9A | |
| SCHEMBL20477095 | 0.79 | SMN1; SMN2 (0.57) | P2RX7NPC1RAB9ACNR2TAS1R3 | |
| SCHEMBL12476380 | 0.78 | CNR1 (0.71) | NPC1CNR2CNR1 | |
| SCHEMBL8297083 | 0.78 | HPGD (0.57) | P2RX7NPC1RAB9A | |
| SCHEMBL28729042 | 0.78 | CNR2 (0.49) | NPC1RAB9ACNR2CNR1HTR4 | |
| SCHEMBL12697364 | 0.76 | CNR2 (0.56) | CNR2CNR1 | |
| SCHEMBL13163160 | 0.76 | MEN1 (0.51) | P2RX7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195497-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-113195497-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |