Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 16/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.58 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162900 | 0.89 | CHRM1 (0.65) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL28600527 | 0.87 | CHRM1 (0.57) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL28982241 | 0.86 | CHRM1 (0.56) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL28607828 | 0.84 | P2RX7 (0.52) | HTR4 | |
| SCHEMBL22122848 | 0.80 | CHRM1 (0.58) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL28503120 | 0.79 | P2RX7 (0.47) | — | |
| SCHEMBL22123764 | 0.79 | TAS1R3 (0.57) | HTR4 | |
| SCHEMBL13543095 | 0.78 | CHRM1 (0.62) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL8297083 | 0.78 | HPGD (0.57) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL7213953 | 0.77 | HTR4 (0.61) | CHRM1CHRM2CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195497-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-113195497-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |