Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381551 | 0.86 | — | — | |
| SCHEMBL2182098 | 0.82 | — | — | |
| SCHEMBL13044543 | 0.82 | — | — | |
| SCHEMBL96256 | 0.77 | — | — | |
| SCHEMBL12216595 | 0.77 | — | — | |
| SCHEMBL2179467 | 0.77 | — | — | |
| SCHEMBL21114321 | 0.75 | ADH1A (0.41) | — | |
| SCHEMBL21114287 | 0.75 | ADH1A (0.41) | — | |
| SCHEMBL7136561 | 0.75 | ADH1A (0.41) | — | |
| SCHEMBL21114300 | 0.75 | ADH1A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084507-A2 | PROCESS FOR THE PREPARATION OF N-METHYL-2-[3-(1-METHYL-4-PIPERIDYL)-1H-INDOL-5-YL]-ETHANESULFONAMIDE AND ITS ACID ADDITION SALTS | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2010-07-29 | — | — | WO | claimed |
| CN-103221404-B | Can be used as the unsaturated nitrogen heterogeneous ring compound of PDE10 inhibitor | AMGEN INC. (US) | 2015-12-16 | — | — | CN | disclosed |
| CN-103221404-A | Nitrogen heterocyclic compounds useful as PDE10 inhibitors | AMGEN INC | 2013-07-24 | — | — | CN | disclosed |
| CN-101316823-B | 2,4, 5-triphenylimidazoline derivatives as inhibitors of the interaction between p53 and MDM2 proteins for use as anticancer agents | HOFFMANN LA ROCHE | 2013-05-22 | — | — | CN | disclosed |
| WO-2010084507-A2 | PROCESS FOR THE PREPARATION OF N-METHYL-2-[3-(1-METHYL-4-PIPERIDYL)-1H-INDOL-5-YL]-ETHANESULFONAMIDE AND ITS ACID ADDITION SALTS | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2010-07-29 | — | — | WO | disclosed |
| CN-101316823-A | 2,4, 5-triphenylimidazoline derivatives as inhibitors of the interaction between p53 and MDM2 proteins for use as anticancer agents | HOFFMANN LA ROCHE (CH) | 2008-12-03 | — | — | CN | disclosed |
| US-4442107-A | HYPOTENSIVE, ANTIARRHYTHMIA | ACF CHEMIEFARMA N.V. (NL) | 1984-04-10 | — | — | US | disclosed |