SCHEMBL2860802

SCHEMBL2860802

O=C(O)C(C1=CCCC1)C1=CCCC1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
TBXAS1 P24557 1/20 0.34
ACMSD Q8TDX5 1/20 0.33
GRIA1 P42261 1/20 0.32
GRIA3 P42263 1/20 0.32
GRIA4 P48058 1/20 0.32
GRIK5 Q16478 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
HIF1A Q16665 1/20 0.31
HCAR3 P49019 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23430236 0.82 HDAC4 (0.38) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL36366 0.79 HDAC3 (0.33) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL10362582 0.79 NPSR1 (0.50) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL1995274 0.79 HPGD (0.38) TBXAS1ACMSDNPSR1
SCHEMBL1512895 0.78 GRIA1 (0.36) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL9623341 0.78 PTGS1 (0.36) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL6277305 0.77 HDAC3 (0.32) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL1469166 0.77 HDAC3 (0.32) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL2919621 0.76 HDAC4 (0.39) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL10171591 0.74 HDAC4 (0.38) HDAC4HDAC2HDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2106855-B1 Heterogeneous catalyst and process for producing oxirane compound with the catalyst NISSAN CHEMICAL IND LTD (JP) 2012-07-11 EP disclosed
US-7700789-B2 Heterogeneous catalyst and process for producing oxirane compound with the catalyst NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-04-20 US disclosed
EP-1632291-B1 HETEROGENEOUS CATALYST AND PROCESS FOR PRODUCING OXIRANE COMPOUND WITH THE CATALYST NISSAN CHEMICAL IND LTD (JP) 2009-12-16 EP disclosed
EP-2106855-A1 Heterogeneous catalyst and process for producing oxirane compound with the catalyst Nissan Chemical Industries, Ltd. (JP) 2009-10-07 EP disclosed
US-20090082583-A1 Heterogeneous catalyst and process for producing oxirane compound with the catalyst NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-26 US disclosed
US-20070093667-A1 Heterogeneous catalyst and process for producing oxirane compound with the catalyst NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-26 US disclosed
EP-1632291-A1 HETEROGENEOUS CATALYST AND PROCESS FOR PRODUCING OXIRANE COMPOUND WITH THE CATALYST Nissan Chemical Industries, Ltd. (JP) 2006-03-08 EP disclosed
CN-1177782-C Reactive coalescents ������������� 2004-12-01 CN disclosed
US-6048664-A Energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material LUCENT TECHNOLOGIES, INC. (US) 2000-04-11 US disclosed
CN-1195656-A Reactive coalescents ROHM & HAAS (US) 1998-10-14 CN disclosed
US-4855488-A Process for the preparation of dicyclopentenol esters HUELS AKTIENGESELLSCHAFT (DE) 1989-08-08 US disclosed
EP-0300162-A2 Method for the production of dicyclopentenol esters HÜLS AKTIENGESELLSCHAFT (DE) 1989-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093667-A1 Heterogeneous catalyst and process for producing oxirane compound with the catalyst OXGR1, OXER1, OGFOD1 HDAC4 1656/4885HDAC2 215/4885HDAC8 1318/4885
US-20090082583-A1 Heterogeneous catalyst and process for producing oxirane compound with the catalyst OXGR1, OGFOD1, OGDH HDAC4 1259/4885HDAC2 167/4885HDAC8 1010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.