Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28563728 | 0.88 | AURKA (0.47) | AURKAAURKBKDM4EMEN1KMT2A | |
| SCHEMBL28913232 | 0.86 | ALDH1A1 (0.51) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28912506 | 0.80 | KDM4E (0.53) | AURKAAURKBKDM4EMEN1KMT2A | |
| SCHEMBL28350370 | 0.77 | KDM4E (0.75) | AURKAAURKBKDM4EMEN1KMT2A | |
| SCHEMBL30064616 | 0.77 | KDM4E (0.75) | AURKAAURKBKDM4EMEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL28608280 | 0.74 | KDM4E (0.51) | AURKAAURKBKDM4EMEN1KMT2A | |
| SCHEMBL28565686 | 0.73 | ALDH1A1 (0.50) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28494948 | 0.73 | AURKA (0.57) | AURKAAURKBKDM4EMEN1KMT2A | |
| SCHEMBL27719836 | 0.72 | KDM4E (0.40) | KDM4ESMN1; SMN2PLA2G2AMAPTALDH1A1 | |
| SCHEMBL23674306 | 0.72 | AURKA (0.63) | AURKAAURKBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106380446-B | Synthesis method of quinoline-2 formate derivative | 南阳师范学院 | 2021-06-18 | — | — | CN | disclosed |