Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550497 | 0.91 | GRM2 (0.42) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL28913232 | 0.88 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL28560877 | 0.85 | ACACA (0.44) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL28563728 | 0.85 | AURKA (0.47) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL28550126 | 0.85 | MAPK1 (0.50) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL28550499 | 0.85 | PRNP (0.41) | ALDH1A1MAPTTDP1DHODH | |
| SCHEMBL28566549 | 0.85 | PRNP (0.41) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28912506 | 0.79 | KDM4E (0.53) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL28559916 | 0.79 | TNKS (0.41) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL28559495 | 0.79 | LTB4R (0.46) | MEN1KMT2AMAPK1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106366035-B | Synthesis method of quinoline derivative | 南阳师范学院 | 2021-05-07 | — | — | CN | disclosed |