Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601685 | 0.81 | L3MBTL1 (0.53) | MAPTL3MBTL1TDP1NPSR1 | |
| SCHEMBL28603322 | 0.80 | ABCB1 (0.52) | HTR1ADRD2ABCB1ABCG2L3MBTL1 | |
| SCHEMBL23881678 | 0.80 | HTR1A (0.63) | HTR1ADRD2ABCB1GAAMGLL | |
| SCHEMBL8290989 | 0.78 | TAAR1 (0.40) | MAPTL3MBTL1TDP1 | |
| SCHEMBL10784832 | 0.77 | HTR1A (0.73) | HTR1ADRD2ABCB1GAAMGLL | |
| SCHEMBL1894256 | 0.77 | HTR1A (0.67) | HTR1ADRD2ABCB1GAAMGLL | |
| SCHEMBL27714342 | 0.75 | HTR1A (0.65) | HTR1ADRD2ABCB1GAAMGLL | |
| SCHEMBL26698909 | 0.74 | L3MBTL1 (0.54) | GAAMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL1412912 | 0.74 | HTR1A (0.73) | HTR1ADRD2ABCB1GAAMGLL | |
| Formaldehyde SCHEMBL27699996 | 0.74 | HTR1A (0.62) | HTR1ADRD2ABCB1GAAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166182-A | Aminopeptidase A inhibitor and pharmaceutical composition comprising the same | 量子基因公司 | 2021-07-23 | — | — | CN | disclosed |