SCHEMBL2860864

SCHEMBL2860864

CCCCCSc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
MAPK1 P28482 1/20 0.61
PLK1 P53350 1/20 0.49
KDM4E B2RXH2 1/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
SOAT1 P35610 6/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8483918 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3
SCHEMBL5168141 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3
SCHEMBL8484849 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3
SCHEMBL8487585 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3
SCHEMBL15271204 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3
SCHEMBL2792353 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3
SCHEMBL8082721 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3
SCHEMBL58281 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3
SCHEMBL5694452 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3
SCHEMBL27390190 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1PLK1KDM4EHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558948-A1 SILOXANE OPTICAL WAVEGUIDES Polyset Company, Inc. (US) 2005-08-03 EP claimed
US-6832036-B2 Siloxane optical waveguides POLYSET COMPANY, INC. 2004-12-14 US claimed
WO-2004034104-A1 SILOXANE OPTICAL WAVEGUIDES POLYSET COMPANY INC. (US) 2004-04-22 WO claimed
US-20040076391-A1 Siloxane optical waveguides POLYSET CHEMICAL COMPANY INC. (US) 2004-04-22 US claimed
EP-4499634-A1 SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS Nikang Therapeutics, Inc. (US) 2025-02-05 EP disclosed
WO-2023192801-A1 SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS NIKANG THERAPEUTICS, INC. (US) 2023-10-05 WO disclosed
US-20230004084-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-01-05 US disclosed
EP-4023635-A1 ACTIVE LIGHT RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTIVE LIGHT RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, METHOD FOR FORMING PATTERN, AND METHOD FOR PRODUCING ELECTRONIC DEVICE FUJIFILM Corporation (JP) 2022-07-06 EP disclosed
WO-2021041583-A1 COMPOUNDS TO IDENTIFY BETA-LACTAMASES, AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-03-04 WO disclosed
EP-3366674-B1 PYRIDINE COMPOUND SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
WO-2020140956-A1 PROCESS FOR PREPARING SULFONAMIDE COMPOUNDS ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) 2020-07-09 WO disclosed
CN-107722049-B Preparation and application of novel ionic binuclear Schiff base titanium complex 山西医科大学 2020-06-30 CN disclosed
JP-2000198768-A 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE/MITICIDE KUMIAI CHEM IND CO LTD 2000-07-18 JP disclosed
US-5164113-A Ferroelectric, polarization promoters MITSUBISHI RAYON CO., LTD. (JP) 1992-11-17 US disclosed
EP-0396410-A2 Optical active compound and liquid crystal composition MITSUBISHI RAYON CO., LTD. (JP) 1990-11-07 EP disclosed
EP-0233342-B1 1,3-DIOXOL-2-ONE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS SUBSTRATE FOR MEASUREMENT OF ARYLESTERASE ACTIVITY KANEBO, LTD. (JP) 1989-04-19 EP disclosed
US-4777267-A DIAGNOSIS OF LIVER DISORDERS KANEBO LTD. (JP) 1988-10-11 US disclosed
EP-0233342-A1 1,3-dioxol-2-one derivatives, process for production thereof, and use thereof as substrate for measurement of arylesterase activity KANEBO, LTD. (JP) 1987-08-26 EP disclosed
US-4391959-A Polymerization of isobutylene BASF AKTIENGESELLSCHAFT (DE) 1983-07-05 US disclosed
US-4055652-A 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof SYNTEX (U.S.A.) INC. (US) 1977-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230004084-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN H1-10, H1-0, H1-4 ALDH1A1 518/4885MAPK1 1996/4885PLK1 4760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.