SCHEMBL58281

SCHEMBL58281

CCCCCCCCCCSc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
MAPK1 P28482 1/20 0.58
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HDAC9 Q9UKV0 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
PLK1 P53350 1/20 0.51
KDM4E B2RXH2 1/20 0.47
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
SOAT1 P35610 8/20 0.47
PTGS2 P35354 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27390190 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL5168141 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL15271204 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL8483918 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL8487585 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL8484849 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL8082721 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL2792353 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL5694452 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1
SCHEMBL135352 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559884-B2 Binder-consolidated textile fabric, method for its manufacture and its use JOHNS MANVILLE (US) 2026-02-24 US disclosed
EP-3299514-B1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE JOHNS MANVILLE EUROPE GMBH (DE) 2024-11-06 EP disclosed
CN-110835506-B Adhesive-reinforced textile fabric, method for the production thereof and use thereof 约翰斯曼维尔公司 2022-11-04 CN disclosed
CN-107869054-B Adhesive-reinforced textile, method for the production thereof and use thereof 约翰斯曼维尔欧洲有限公司 2022-05-03 CN disclosed
EP-3779015-B1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE JOHNS MANVILLE (US) 2021-12-08 EP disclosed
US-10934460-B2 Binder-consolidated textile fabrics and methods of their manufacture and use JOHNS MANVILLE (US) 2021-03-02 US disclosed
EP-3779015-A1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE Johns Manville (US) 2021-02-17 EP disclosed
CN-110835506-A Adhesive-reinforced textile fabric, method for the production thereof and use thereof 约翰斯曼维尔公司 2020-02-25 CN disclosed
US-20200056327-A1 Binder-consolidated textile fabric, method for its manufacture and its use JOHNS MANVILLE 2020-02-20 US disclosed
US-10472546-B2 Binder-consolidated textile fabrics and methods of their manufacture and use JOHNS MANVILLE (US) 2019-11-12 US disclosed
US-4268337-A Sheet molding material produced by associating a layer comprising a photopolymerizable material with layers comprising thermosetting resins ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-05-19 US disclosed
US-4262072-A ABRASION RESISTANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-04-14 US disclosed
WO-1981000536-A1 OPHTHALMIC LENS BLANK WITH PROTECTIVE COATING MINNESOTA MINING & MFG (US) 1981-03-05 WO disclosed
US-4249011-A CURING AGENTS FOR ADDITION PHOTOPOLYMERIZATION MINNESOTA MINING AND MANUFACTURING COMPANY 1981-02-03 US disclosed
WO-1981000011-A1 POLY(ETHYLENICALLY UNSATURATED ALKOXY)HETEROCYCLIC COMPOUNDS AND CROSSLINKED POLYMERIC COATINGS MINNESOTA MINING & MFG (US) 1981-01-08 WO disclosed
WO-1981000012-A1 IRRADIATION OF POLYACRYLATE COMPOSITIONS IN AIR MINNESOTA MINING & MFG (US) 1981-01-08 WO disclosed
US-4214026-A PHOTOPOLYMERIZABLE RESIN ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-22 US disclosed
US-4164421-A Photocurable composition containing an o-quinonodiazide for printing plate FUJI PHOTO FILM CO., LTD. (JP) 1979-08-14 US disclosed
US-4113487-A LAYER OF PHOTO-SETTING AND EXPANDABLE RESIN EXPOSED TO PARTIALLY SCREENED LIGHT TOPPAN PRINTING CO., LTD. (JP) 1978-09-12 US disclosed
US-4085018-A FROM POLYEPOXIDE OF DIHYDROXYDIPHENYLMETHANE AND EPICHLOROHYDRIN AND UNSATURATED MONOBASIC ACID DAINIPPON INK AND CHEMICALS, INC. (JA) 1978-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559884-B2 Binder-consolidated textile fabric, method for its manufacture and its use SEM1, SMCHD1, SMC4 ALDH1A1 1097/4885MAPK1 1812/4885HDAC3 998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.