SCHEMBL28608927

SCHEMBL28608927

C[C@@H]1COC(CBr)(c2ccc(Br)cc2)O1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
TAAR1 Q96RJ0 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28605862 1.00 GRIN1 (0.32) GRIN1GRIN2ATAAR1LMNA
SCHEMBL28604802 0.87 CHRNA1 (0.37) GRIN1GRIN2A
SCHEMBL28604796 0.87 CHRNA1 (0.37) GRIN1GRIN2A
SCHEMBL28606554 0.86 SLC6A3 (0.36) GRIN1GRIN2A
SCHEMBL28602336 0.86 SLC6A3 (0.36) GRIN1GRIN2A
SCHEMBL28599785 0.85 GRIN1 (0.43) GRIN1GRIN2A
SCHEMBL28603091 0.85 GRIN1 (0.43) GRIN1GRIN2A
SCHEMBL28604612 0.83 TAAR1 (0.32) GRIN1GRIN2ATAAR1
SCHEMBL10850741 0.83 SLC6A2 (0.39) GRIN1GRIN2A
SCHEMBL28605970 0.83 MAOB (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234066-A Propiconazole-like compound and preparation method and application thereof 浙江工业大学 2021-08-10 CN disclosed