SCHEMBL28606554

SCHEMBL28606554

C[C@H]1COC(CBr)(c2ccc(F)cc2)O1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.36
SLC6A2 P23975 2/20 0.36
CHRNA1 P02708 1/20 0.36
CHRNG P07510 1/20 0.36
CHRNB1 P11230 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
CHRND Q07001 1/20 0.36
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.36
EGFR P00533 1/20 0.35
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
HSD11B1 P28845 1/20 0.31
ALDH1A1 P00352 1/20 0.30
SLC6A4 P31645 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28602336 1.00 SLC6A3 (0.36) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL28605862 0.86 GRIN1 (0.32) GRIN1GRIN2A
SCHEMBL28604796 0.86 CHRNA1 (0.37) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL28608927 0.86 GRIN1 (0.32) GRIN1GRIN2A
SCHEMBL28604802 0.86 CHRNA1 (0.37) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL28599785 0.84 GRIN1 (0.43) GRIN1GRIN2A
SCHEMBL28603091 0.84 GRIN1 (0.43) GRIN1GRIN2A
SCHEMBL28605867 0.84 SLC6A3 (0.38) SLC6A3SLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL28603088 0.84 MAOA (0.41) SLC6A3SLC6A2MAOBMAOASLC6A4
SCHEMBL28617612 0.84 MAOA (0.41) SLC6A3SLC6A2MAOBMAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234066-A Propiconazole-like compound and preparation method and application thereof 浙江工业大学 2021-08-10 CN disclosed