Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 4/20 | 0.49 |
| ▸ | CCKBR | P32239 | 4/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.49 |
| ▸ | PTPRB | P23467 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607155 | 0.88 | SCN9A (0.44) | HDAC8CTSSCTSKCTSBCTSL | |
| SCHEMBL28605021 | 0.86 | MEN1 (0.48) | CTSSCTSKCTSBCTSL | |
| SCHEMBL28603103 | 0.82 | IDO1 (0.41) | CTSSCTSKSCN9ABCL2 | |
| SCHEMBL22410268 | 0.82 | IDO1 (0.38) | HDAC8CTSSCTSKCTSLSCN9A | |
| SCHEMBL22410271 | 0.82 | IDO1 (0.38) | HDAC8CTSSCTSKCTSLSCN9A | |
| SCHEMBL3944495 | 0.82 | HDAC8 (0.72) | HDAC8CTSSCTSKCTSBCTSL | |
| SCHEMBL9610766 | 0.82 | HDAC8 (0.72) | HDAC8CTSSCTSKCTSBCTSL | |
| SCHEMBL22126009 | 0.81 | AAK1 (0.40) | HDAC8CTSSCTSKCTSBCTSL | |
| SCHEMBL29894827 | 0.81 | AAK1 (0.40) | HDAC8CTSSCTSKCTSBCTSL | |
| SCHEMBL28609000 | 0.81 | CTSS (0.48) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | LEO PHARMA A/S (DK) | 2022-07-05 | — | — | US | disclosed |
| CN-113164448-A | Amino acid anilines as small molecule modulators of IL-17 | 利奥制药有限公司 | 2021-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | IL17A, IL15, IL2 | HDAC8 666/4885CTSS 757/4885CTSK 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.