Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 10/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602379 | 0.85 | GPR119 (0.44) | USP30GPR119IDO1MEN1KMT2A | |
| SCHEMBL28614617 | 0.85 | GPR119 (0.45) | AAK1FPR2GPR119IDO1MEN1 | |
| SCHEMBL28604647 | 0.84 | GPR119 (0.46) | AAK1FPR2GPR119IDO1MEN1 | |
| SCHEMBL28604646 | 0.84 | GPR119 (0.46) | AAK1FPR2GPR119IDO1MEN1 | |
| SCHEMBL28605021 | 0.83 | MEN1 (0.48) | CTSSCTSKAAK1FPR2GPR119 | |
| SCHEMBL27192711 | 0.82 | CTSS (0.58) | CTSSCTSKUSP30AAK1FPR2 | |
| SCHEMBL27192706 | 0.82 | CTSS (0.58) | CTSSCTSKUSP30AAK1FPR2 | |
| SCHEMBL28607177 | 0.82 | GPR119 (0.46) | AAK1FPR2GPR119IDO1MEN1 | |
| SCHEMBL28609015 | 0.81 | HDAC8 (0.53) | CTSSCTSK | |
| SCHEMBL28605926 | 0.78 | MEN1 (0.46) | CTSSCTSKAAK1GPR119IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | LEO PHARMA A/S (DK) | 2022-07-05 | — | — | US | disclosed |
| CN-113164448-A | Amino acid anilines as small molecule modulators of IL-17 | 利奥制药有限公司 | 2021-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | IL17A, IL15, IL2 | CTSS 757/4885CTSK 441/4885USP30 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.