SCHEMBL2860913

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31632976	0.90	MAP2K4 (0.72)	MAP2K4NTRK1TTKMAPK1MAP2K7
	SCHEMBL31172414	0.87	MAP3K8 (0.54)	MAP2K4NTRK1MEN1KMT2A
	SCHEMBL2866811	0.85	MAP2K4 (0.55)	MAP2K4TTKMAPK8MAPK1CSNK1D
	SCHEMBL2858476	0.85	MAP2K4 (0.68)	MAP2K4NTRK1TTKMAPK1MAPK3
	SCHEMBL5801740	0.84	MAP2K4 (0.65)	MAP2K4NTRK1TTKMAPK8MAPK1
	Ethylene SCHEMBL27536148	0.82	MAP2K4 (0.65)	MAP2K4NTRK1TTKMAPK1MAPK3
	SCHEMBL27558524	0.82	MAP2K4 (0.54)	MAP2K4NTRK1MAPK1MAP2K7CSNK1D
	SCHEMBL2869817	0.81	MAP2K4 (0.54)	MAP2K4NTRK1TTKMAPK1CSNK1D
	SCHEMBL2868599	0.81	MAP2K4 (0.57)	MAP2K4TTKMAPK8MAPK1CSNK1D
	SCHEMBL2864413	0.81	MAP2K4 (0.60)	MAP2K4NTRK1TTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.