SCHEMBL2864413

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9986229	0.84	MAPK1 (0.58)	MAP2K4
	SCHEMBL2863052	0.84	MAP2K4 (0.62)	MAP2K4LRRK2IDO1PIM1CDK7
	SCHEMBL2860913	0.81	MAP2K4 (0.61)	MAP2K4TTKNTRK1
	SCHEMBL2866811	0.81	MAP2K4 (0.55)	MAP2K4LRRK2TTK
	SCHEMBL7809400	0.80	CYP11B1 (0.59)	CYP19A1CYP11B1CYP11B2NR4A2SLC2A1
	SCHEMBL2861069	0.79	ALPL (0.54)	MAP2K4CYP19A1CYP11B1CYP11B2
	SCHEMBL12594228	0.79	CYP19A1 (0.54)	CYP19A1CYP11B1CYP11B2PIM1NR4A2
	SCHEMBL1501529	0.78	KDM4E (0.55)	MAP2K4DYRK1AALDH1A1
	SCHEMBL2860104	0.78	PIM1 (0.53)	MAP2K4CYP19A1CYP11B1CYP11B2LRRK2
	SCHEMBL2863569	0.78	LRRK2 (0.56)	MAP2K4LRRK2PIM1AXLNTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.