Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 7/20 | 0.34 |
| ▸ | RAB9A | P51151 | 7/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 2/20 | 0.31 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28622749 | 1.00 | TP53 (0.36) | TP53ALOX15NPC1RAB9AMTNR1A | |
| SCHEMBL27415382 | 0.88 | ABL1 (0.34) | NPC1RAB9AALDH1A1 | |
| SCHEMBL27415416 | 0.87 | NPC1 (0.32) | NPC1RAB9AALDH1A1 | |
| SCHEMBL21597854 | 0.85 | TP53 (0.41) | TP53ALOX15NPC1RAB9AMTNR1A | |
| SCHEMBL21603867 | 0.82 | TP53 (0.39) | TP53ALOX15NPC1RAB9AMTNR1A | |
| SCHEMBL21603763 | 0.78 | TP53 (0.39) | TP53ALOX15NPC1RAB9AALDH1A1 | |
| SCHEMBL21597801 | 0.76 | TP53 (0.40) | TP53ALOX15NPC1RAB9AALDH1A1 | |
| SCHEMBL21597427 | 0.76 | TBXAS1 (0.46) | TP53ALOX15NPC1RAB9AALDH1A1 | |
| SCHEMBL21603764 | 0.76 | ALDH1A1 (0.54) | TP53ALOX15NPC1RAB9AALDH1A1 | |
| SCHEMBL21603808 | 0.75 | EPHX2 (0.50) | NPC1RAB9AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |