Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | XDH | P47989 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA7 | P43166 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.49 |
| ▸ | TPMT | P51580 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821501 | 0.89 | LMNA (0.60) | LMNAKDM4EXDHPOLBGAA | |
| SCHEMBL29853860 | 0.89 | LMNA (0.60) | LMNAKDM4EXDHPOLBGAA | |
| SCHEMBL289398 | 0.85 | LMNA (0.69) | LMNAKDM4EXDHPOLBGAA | |
| SCHEMBL27732334 | 0.82 | KDM4E (0.71) | LMNAKDM4EXDHPOLBGAA | |
| SCHEMBL28613409 | 0.81 | LCK (0.50) | LMNAKDM4EXDHPOLBGAA | |
| SCHEMBL29093744 | 0.81 | KDM4E (0.51) | LMNAKDM4EXDHPOLBGAA | |
| SCHEMBL21821500 | 0.81 | CA1 (0.54) | LMNAKDM4EPOLBGAAFUT7 | |
| SCHEMBL26579409 | 0.79 | LMNA (0.60) | LMNAKDM4EXDHPOLBGAA | |
| SCHEMBL22828496 | 0.77 | CA1 (0.54) | LMNAKDM4EXDHPOLBGAA | |
| SCHEMBL731509 | 0.77 | KDM4E (0.58) | LMNAKDM4EXDHPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-113039182-A | Inhibitors of YAP/TAZ-TEAD interaction and their use in cancer treatment | 伊文蒂瓦公司 | 2021-06-25 | — | — | CN | disclosed |