Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808280 | 0.90 | MAPT (0.47) | LCKFYNKDM4EALDH1A1MAPT | |
| SCHEMBL21821414 | 0.90 | MAPT (0.47) | LCKFYNKDM4EALDH1A1MAPT | |
| SCHEMBL21821412 | 0.88 | CA12 (0.58) | LCKFYNKDM4EALDH1A1CA12 | |
| SCHEMBL30808277 | 0.88 | CA12 (0.58) | LCKFYNKDM4EALDH1A1CA12 | |
| SCHEMBL731344 | 0.86 | MAPT (0.53) | KDM4EALDH1A1MAPTCA12CA1 | |
| SCHEMBL28609486 | 0.81 | LMNA (0.56) | LCKFYNKDM4EALDH1A1MAPT | |
| SCHEMBL29093744 | 0.80 | KDM4E (0.51) | LCKFYNKDM4EALDH1A1MAPT | |
| SCHEMBL28617598 | 0.80 | NOTUM (0.37) | LCKFYNKDM4EALDH1A1MAPT | |
| SCHEMBL310059 | 0.79 | MAPT (0.60) | LCKFYNKDM4EALDH1A1MAPT | |
| SCHEMBL731509 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-113039182-A | Inhibitors of YAP/TAZ-TEAD interaction and their use in cancer treatment | 伊文蒂瓦公司 | 2021-06-25 | — | — | CN | disclosed |