Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.56 |
| ▸ | CSF1R | P07333 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788245 | 0.88 | CSF1R (0.56) | PDE4BCSF1RSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4761193 | 0.85 | CSF1R (0.72) | PDE4BCSF1R | |
| SCHEMBL30864154 | 0.85 | CSF1R (0.72) | PDE4BCSF1R | |
| SCHEMBL28623902 | 0.85 | CSF1R (0.66) | CSF1RALDH1A1NUDT1 | |
| SCHEMBL28613693 | 0.82 | CSF1R (0.68) | PDE4BCSF1RMAPTTP53NUDT1 | |
| SCHEMBL11244977 | 0.81 | ALDH1A1 (0.78) | PDE4BSMN1; SMN2KDM4EALDH1A1RXFP1 | |
| Hydrochloric Acid SCHEMBL11254237 | 0.80 | ALDH1A1 (0.80) | PDE4BSMN1; SMN2KDM4EALDH1A1RXFP1 | |
| SCHEMBL28623357 | 0.80 | HAVCR2 (0.51) | SMN1; SMN2MAPTTP53NUDT1 | |
| SCHEMBL30436929 | 0.79 | POLB (0.59) | PDE4BCSF1RKDM4EALDH1A1MAPT | |
| SCHEMBL528668 | 0.78 | KMT2A (0.58) | CSF1RSMN1; SMN2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135852-B | Preparation method of 4-aminoquinoline compound | 中国科学院长春应用化学研究所 | 2023-06-20 | — | — | CN | disclosed |
| CN-113135852-A | Preparation method of 4-aminoquinoline compound | 中国科学院长春应用化学研究所 | 2021-07-20 | — | — | CN | disclosed |