Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31248091 | 0.91 | MAPT (0.62) | PTGER4KDM4EDRD2TBXA2RHTT | |
| SCHEMBL28605584 | 0.91 | MAPT (0.62) | PTGER4KDM4EDRD2TBXA2RHTT | |
| SCHEMBL31247978 | 0.89 | TP53 (0.63) | PTGER4KDM4EDRD2TBXA2RGAA | |
| SCHEMBL28596201 | 0.86 | DRD2 (0.71) | PTGER4KDM4EDRD2TBXA2RHTT | |
| SCHEMBL28591480 | 0.86 | HTT (0.59) | PTGER4KDM4EHTTGAAALDH1A1 | |
| SCHEMBL31472959 | 0.86 | HTT (0.59) | PTGER4KDM4EHTTGAAALDH1A1 | |
| SCHEMBL28609161 | 0.84 | HDAC1 (0.57) | PTGER4KDM4EDRD2TBXA2RGAA | |
| SCHEMBL17938355 | 0.80 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL17938347 | 0.79 | PTGER4 (0.86) | PTGER4 | |
| SCHEMBL11525289 | 0.78 | KDM4E (0.59) | KDM4EHTTGAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166073-A | Benzoheterocyclic compounds and compositions for preventing or treating cancer diseases containing the same as active ingredient | 启明大学校产学协力团 | 2021-07-23 | — | — | CN | disclosed |