Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | TDP2 | O95551 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606058 | 0.90 | CRBN (0.53) | CYP11B1CYP11B2CYP1A2TDP2CRBN | |
| SCHEMBL29899622 | 0.82 | CYP11B1 (0.79) | CYP11B1CYP11B2CYP1A2TDP2CYP2C9 | |
| SCHEMBL3659028 | 0.82 | CYP11B1 (0.79) | CYP11B1CYP11B2CYP1A2TDP2CYP2C9 | |
| SCHEMBL28607397 | 0.82 | CRBN (0.48) | TDP2CRBNFABP7FABP3FABP5 | |
| SCHEMBL28918955 | 0.82 | FABP7 (0.52) | TDP2CRBNFABP7FABP3FABP5 | |
| SCHEMBL28595556 | 0.81 | GRIA1 (0.53) | CYP11B1CYP11B2CYP1A2TDP2PDE3B | |
| SCHEMBL29016191 | 0.74 | CRBN (0.54) | TDP2CRBNFABP7FABP3FABP5 | |
| SCHEMBL29849827 | 0.73 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP1A2TDP2CYP2C9 | |
| SCHEMBL748904 | 0.73 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP1A2TDP2CYP2C9 | |
| SCHEMBL29899595 | 0.73 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP1A2TDP2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-A | Agent for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2021-07-30 | — | — | CN | disclosed |