Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 7/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606058 | 0.90 | CRBN (0.53) | CRBNFABP7FABP5FABP3TDP2 | |
| SCHEMBL28918955 | 0.84 | FABP7 (0.52) | CRBNFABP7FABP5FABP3TDP2 | |
| SCHEMBL4467581 | 0.84 | CRBN (0.57) | CRBNRXRARXRBRXRGFABP7 | |
| SCHEMBL28610367 | 0.82 | CYP11B1 (0.56) | CRBNFABP7FABP5FABP3TDP2 | |
| SCHEMBL28595556 | 0.81 | GRIA1 (0.53) | CRBNTDP2PGRGRIA1CACNG8 | |
| SCHEMBL29016191 | 0.74 | CRBN (0.54) | CRBNFABP7FABP5FABP3TDP2 | |
| SCHEMBL24721352 | 0.74 | PGR (0.63) | CRBNRXRARXRBRXRGTDP2 | |
| SCHEMBL26793104 | 0.73 | KIF11 (0.56) | CRBNRXRARXRBRXRGBRD4 | |
| SCHEMBL4463670 | 0.72 | KDR (0.60) | — | |
| SCHEMBL6215696 | 0.72 | CRBN (0.72) | CRBNFABP7FABP5FABP3TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-A | Agent for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2021-07-30 | — | — | CN | disclosed |