Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.54 |
| ▸ | TDP2 | O95551 | 5/20 | 0.45 |
| ▸ | FABP7 | O15540 | 2/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxindole SCHEMBL28593104 | 0.88 | AHR (0.50) | CRBNGRIA1CACNG8BRD4CREBBP | |
| SCHEMBL28606058 | 0.83 | CRBN (0.53) | CRBNTDP2FABP7FABP5FABP3 | |
| SCHEMBL28606054 | 0.82 | AHR (0.40) | TDP2GRIA1CACNG8CREBBPLMNA | |
| SCHEMBL29016211 | 0.79 | CRBN (0.53) | CRBNTDP2FABP7FABP5FABP3 | |
| SCHEMBL4471265 | 0.77 | RAB9A (0.51) | CREBBPKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL6215696 | 0.76 | CRBN (0.72) | CRBNTDP2FABP7FABP5FABP3 | |
| SCHEMBL4408889 | 0.76 | TDP2 (0.65) | CRBNTDP2FABP7FABP5FABP3 | |
| SCHEMBL29016225 | 0.75 | CRBN (0.54) | CRBNTDP2FABP7FABP5FABP3 | |
| SCHEMBL28595556 | 0.74 | GRIA1 (0.53) | CRBNTDP2GRIA1CACNG8PGR | |
| SCHEMBL28610367 | 0.74 | CYP11B1 (0.56) | CRBNTDP2FABP7FABP5FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |