SCHEMBL28610771

SCHEMBL28610771

CCCCC(N)[Si](CC)(CC)CC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.40
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
DNM1 Q05193 2/20 0.36
SPHK1 Q9NYA1 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
DPP7 Q9UHL4 1/20 0.32
SLC15A1 P46059 1/20 0.32
TP53 P04637 2/20 0.32
LAP3 P28838 1/20 0.32
CYP2D6 P10635 2/20 0.31
PLA2G1B P04054 1/20 0.31
PLA2G2A P14555 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2005159 0.76 OPRM1 (0.42) OPRM1ALDH1A1TDP1DNM1SPHK1
SCHEMBL4530242 0.74 DPP7 (0.41) OPRM1ALDH1A1TDP1DNM1SPHK1
SCHEMBL27093893 0.72 DNM1 (0.39) OPRM1ALDH1A1TDP1DNM1CA1
SCHEMBL446942 0.72 OPRM1 (0.34) OPRM1ALDH1A1TDP1DNM1
SCHEMBL999839 0.71
SCHEMBL8588077 0.70 OPRM1 (0.37) OPRM1ALDH1A1TDP1DNM1SPHK1
SCHEMBL30445858 0.69 OPRM1 (0.36) OPRM1ALDH1A1TDP1DNM1SPHK1
Ammonia Solution, Strong SCHEMBL17223654 0.69 OPRM1 (0.36) OPRM1ALDH1A1TDP1DNM1SPHK1
SCHEMBL4513263 0.69 OPRM1 (0.46) OPRM1SPHK1SLC1A2SLC1A1TP53
SCHEMBL8586711 0.69 OPRM1 (0.41) OPRM1ALDH1A1TDP1DNM1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096776-B Catalyst-free fast-curing dealcoholized fluorosilicone rubber and preparation method thereof 山东大学 2021-07-09 CN disclosed