SCHEMBL2861096

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2872497	0.83	DYRK1A (0.52)	MAP2K4NTRK1TTKCLK2CLK3
	SCHEMBL6759015	0.82	TAAR1 (0.54)	MAP2K4NTRK1TTKCLK2CLK3
	SCHEMBL2858476	0.81	MAP2K4 (0.68)	MAP2K4NTRK1TTKMAPK1MAPKAPK3
	SCHEMBL4151692	0.80	MAP2K4 (0.46)	MAP2K4KDM4EMAPK1SMN1; SMN2GRK6
	SCHEMBL6545253	0.79	MAP2K4 (0.52)	MAP2K4NTRK1TTK
	SCHEMBL2856182	0.79	NTRK1 (0.49)	MAP2K4NTRK1MAPK1CLK2CLK3
	Ethylene SCHEMBL27536148	0.79	MAP2K4 (0.65)	MAP2K4NTRK1TTKMAPK1MAPKAPK3
	SCHEMBL6545822	0.78	MAP2K4 (0.44)	MAP2K4NTRK1TTKMAPK1CLK2
	SCHEMBL2871404	0.78	GSK3B (0.54)	NTRK1TTKMAPK1CLK2DYRK1A
	SCHEMBL2869817	0.78	MAP2K4 (0.54)	MAP2K4NTRK1TTKMAPK1MAPKAPK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.