Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 4/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.43 |
| ▸ | TTK | P33981 | 3/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861096 | 0.78 | MAP2K4 (0.51) | MAP2K4NTRK1TTKMAPK1DYRK1A | |
| SCHEMBL6759015 | 0.78 | TAAR1 (0.54) | MAP2K4NTRK1TTKDYRK1ACLK2 | |
| SCHEMBL6545524 | 0.77 | NTRK1 (0.42) | MAP2K4NTRK1TTKMAPK8MAPK1 | |
| SCHEMBL5801740 | 0.76 | MAP2K4 (0.65) | MAP2K4NTRK1TTKMAPK8MAPK1 | |
| SCHEMBL6545253 | 0.75 | MAP2K4 (0.52) | MAP2K4NTRK1TTKMAPK8 | |
| SCHEMBL2872497 | 0.74 | DYRK1A (0.52) | MAP2K4NTRK1TTKDYRK1ACLK2 | |
| SCHEMBL2871404 | 0.74 | GSK3B (0.54) | NTRK1TTKMAPK1DYRK1ACLK2 | |
| SCHEMBL27558704 | 0.73 | TTK (0.56) | MAP2K4NTRK1TTK | |
| SCHEMBL2856182 | 0.72 | NTRK1 (0.49) | MAP2K4NTRK1MAPK1DYRK1ACLK2 | |
| SCHEMBL2858476 | 0.72 | MAP2K4 (0.68) | MAP2K4NTRK1TTKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380576-A1 | NOVEL 1H-INDAZOLE COMPOUND | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |