Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 3/20 | 0.52 |
| ▸ | TTK | P33981 | 13/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759015 | 0.83 | TAAR1 (0.54) | MAP2K4TTKNTRK1 | |
| SCHEMBL6545436 | 0.81 | TTK (0.49) | MAP2K4TTKMAPK8 | |
| SCHEMBL2861096 | 0.79 | MAP2K4 (0.51) | MAP2K4TTKNTRK1 | |
| SCHEMBL2856182 | 0.78 | NTRK1 (0.49) | MAP2K4NTRK1 | |
| SCHEMBL14516332 | 0.76 | AURKA (0.59) | MAP2K4TTKNTRK1 | |
| SCHEMBL6545822 | 0.75 | MAP2K4 (0.44) | MAP2K4TTKNTRK1MAPK8 | |
| SCHEMBL6545185 | 0.74 | MAP2K4 (0.51) | MAP2K4TTKNTRK1MAPK8MAP2K7 | |
| SCHEMBL5801740 | 0.73 | MAP2K4 (0.65) | MAP2K4TTKNTRK1MAPK8MAP2K7 | |
| SCHEMBL2869839 | 0.73 | MAP2K4 (0.61) | MAP2K4TTKNTRK1MAP2K7 | |
| SCHEMBL2872497 | 0.73 | DYRK1A (0.52) | MAP2K4TTKNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380576-A1 | NOVEL 1H-INDAZOLE COMPOUND | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |