Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28756030 | 0.90 | MEN1 (0.46) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL16367415 | 0.88 | MAOB (0.45) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL31376603 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2ABCL9CTNNB1MAOB | |
| SCHEMBL1837096 | 0.79 | CTSK (0.57) | NPC1RAB9ATSHRCYP1A2 | |
| SCHEMBL10959985 | 0.79 | AKR1C3 (0.46) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL28524238 | 0.79 | AKR1C3 (0.46) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL5660737 | 0.77 | MEN1 (0.45) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL23111943 | 0.77 | KMT2A (0.50) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL29602251 | 0.77 | KMT2A (0.50) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL1627903 | 0.77 | KMT2A (0.50) | MEN1KMT2ANPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226377-A | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2021-08-06 | — | — | CN | disclosed |