Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10151401 | 0.90 | ATM (0.45) | ATMCDC7CDK2POLBSMN1; SMN2 | |
| Formamide SCHEMBL28426147 | 0.87 | MAPT (0.41) | ATMCYP2A6RAPGEF4MAPTPDE3B | |
| SCHEMBL31751287 | 0.77 | CYP2A6 (0.47) | ATMCYP2A6CDC7CDK2POLB | |
| Formamide SCHEMBL8533326 | 0.76 | DAO (0.47) | MAPTMEN1KMT2AKDM4ESLC6A2 | |
| SCHEMBL10151406 | 0.75 | MAPT (0.47) | ATMPOLBSMN1; SMN2RAPGEF4MAPT | |
| Formamide SCHEMBL29013060 | 0.75 | DAO (0.46) | MAPTMEN1KMT2AKDM4ESLC6A2 | |
| SCHEMBL19233649 | 0.74 | CDC7 (0.45) | ATMCDC7CDK2POLBSMN1; SMN2 | |
| SCHEMBL19233635 | 0.74 | RAPGEF4 (0.38) | ATMCDC7CDK2POLBSMN1; SMN2 | |
| SCHEMBL10813893 | 0.73 | BRPF1 (0.54) | ATMPOLBSMN1; SMN2RAPGEF4PDE3B | |
| SCHEMBL30167699 | 0.71 | MAPT (0.49) | SMN1; SMN2MAPTKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549069-A | Kinase inhibitor | 重庆复创医药研究有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-113549069-A | Kinase inhibitor | 重庆复创医药研究有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-108779117-B | Kinase inhibitor | 重庆复创医药研究有限公司 | 2021-08-31 | — | — | CN | disclosed |