Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325755 | 0.77 | STAT3 (0.44) | KMT2AGAAALDH1A1MEN1STAT3 | |
| SCHEMBL10572140 | 0.77 | STAT3 (0.44) | KMT2AGAAALDH1A1MEN1STAT3 | |
| SCHEMBL10572152 | 0.77 | STAT3 (0.44) | KMT2AGAAALDH1A1MEN1STAT3 | |
| SCHEMBL1990108 | 0.76 | MEN1 (0.43) | KMT2AGAAALDH1A1MEN1STAT3 | |
| SCHEMBL27618865 | 0.74 | ALDH1A1 (0.42) | KMT2AGAAALDH1A1MEN1STAT3 | |
| SCHEMBL10602209 | 0.74 | MEN1 (0.46) | KMT2AGAAALDH1A1MEN1STAT3 | |
| SCHEMBL20925382 | 0.74 | KMT2A (0.46) | KMT2AGAAALDH1A1MEN1LMNA | |
| SCHEMBL10597710 | 0.73 | MEN1 (0.45) | KMT2AGAAALDH1A1MEN1STAT3 | |
| SCHEMBL10597153 | 0.72 | KMT2A (0.45) | KMT2AGAAALDH1A1MEN1LMNA | |
| SCHEMBL8713527 | 0.72 | ALDH1A1 (0.41) | KMT2AGAAALDH1A1MEN1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164775-A | Polycyclic compounds and methods for rapid accelerated targeted degradation of fibrosarcoma polypeptides | 阿尔维纳斯运营股份有限公司 | 2021-07-23 | — | — | CN | disclosed |