Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 4/20 | 0.37 |
| ▸ | MMP7 | P09237 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 4/20 | 0.37 |
| ▸ | MMP8 | P22894 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28900875 | 0.73 | ELANE (0.39) | ALDH1A1KDM1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL28532387 | 0.72 | ELANE (0.42) | ALDH1A1MMP13LMNAMAPTGAA | |
| SCHEMBL28476459 | 0.68 | SCN9A (0.40) | ALDH1A1GAA | |
| SCHEMBL1557190 | 0.68 | PDE2A (0.44) | ALDH1A1CACNA1BMMP3MMP13MMP2 | |
| SCHEMBL27666836 | 0.68 | CTSK (0.43) | MAPT | |
| SCHEMBL24538113 | 0.67 | ALDH1A1 (0.65) | ALDH1A1KDM1AMAPTSMN1; SMN2HTT | |
| SCHEMBL24537639 | 0.67 | ALDH1A1 (0.65) | ALDH1A1KDM1AMAPTSMN1; SMN2HTT | |
| SCHEMBL6985979 | 0.66 | GAA (0.46) | ALDH1A1MMP1MMP9MMP13LMNA | |
| SCHEMBL12834968 | 0.66 | MAPT (0.46) | ALDH1A1TRPV1LMNAPPARGPPARA | |
| SCHEMBL11991250 | 0.66 | ELANE (0.48) | LMNASMN1; SMN2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164448-A | Amino acid anilines as small molecule modulators of IL-17 | 利奥制药有限公司 | 2021-07-23 | — | — | CN | disclosed |