Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578814 | 0.92 | TERT (0.51) | TERTMEN1ALDH1A1POLBGAA | |
| SCHEMBL28602533 | 0.90 | TERT (0.67) | TERTMEN1ALDH1A1POLBGAA | |
| SCHEMBL28613597 | 0.88 | TERT (0.58) | TERTMEN1ALDH1A1POLBGAA | |
| SCHEMBL28583627 | 0.81 | TERT (0.67) | TERTMEN1ALDH1A1POLBGAA | |
| SCHEMBL1305202 | 0.79 | TERT (0.76) | TERTMEN1ALDH1A1POLBGAA | |
| SCHEMBL28594887 | 0.76 | TERT (0.68) | TERTMAPT | |
| SCHEMBL6366577 | 0.72 | TERT (0.64) | TERTMEN1ALDH1A1POLBGAA | |
| SCHEMBL19329340 | 0.69 | TDP1 (0.64) | MEN1ALDH1A1POLBGAAMAPT | |
| SCHEMBL1304218 | 0.69 | TERT (0.68) | TERTMEN1ALDH1A1POLBGAA | |
| SCHEMBL28569309 | 0.69 | TERT (0.53) | TERTMEN1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456328-B | 11-substituted 1, 6-diazabenzanthrone derivative and synthesis method and application thereof | GUANGXI NORMAL UNIVERSITY (CN) | 2021-06-22 | — | — | CN | disclosed |