Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583627 | 0.80 | TERT (0.67) | TERTMAPTMEN1ALDH1A1POLB | |
| SCHEMBL28568680 | 0.80 | FGFR1 (0.46) | EGFRFGFR1SRC | |
| SCHEMBL28582968 | 0.78 | S100A4 (0.51) | S100A4 | |
| SCHEMBL28578814 | 0.78 | TERT (0.51) | TERTMAPTMEN1ALDH1A1POLB | |
| SCHEMBL11688579 | 0.77 | TERT (0.73) | TERTMAPTMEN1ALDH1A1EGFR | |
| SCHEMBL5605310 | 0.76 | TERT (0.79) | TERTMAPTMEN1ALDH1A1EGFR | |
| Hydrochloric Acid SCHEMBL11691265 | 0.76 | TERT (0.71) | TERTMAPTMEN1ALDH1A1EGFR | |
| SCHEMBL28613597 | 0.75 | TERT (0.58) | TERTMAPTMEN1ALDH1A1POLB | |
| SCHEMBL28602533 | 0.72 | TERT (0.67) | TERTMAPTMEN1ALDH1A1POLB | |
| SCHEMBL5605466 | 0.71 | TERT (0.72) | TERTMAPTMEN1ALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438445-B | 8-substituted 1, 6-diazabenzanthrone derivative and synthesis method and application thereof | GUANGXI NORMAL UNIVERSITY (CN) | 2021-06-22 | — | — | CN | disclosed |