Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.66 |
| ▸ | EP300 | Q09472 | 4/20 | 0.64 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30395182 | 1.00 | CREBBP (0.66) | CREBBPEP300TRIM24BRD4BAZ2B | |
| SCHEMBL28623958 | 0.80 | CREBBP (1.00) | CREBBPEP300TRIM24BRD4BAZ2B | |
| SCHEMBL30393642 | 0.78 | TAF1 (0.67) | CREBBPEP300 | |
| SCHEMBL28619691 | 0.78 | TAF1 (0.67) | CREBBPEP300 | |
| SCHEMBL28624532 | 0.76 | CREBBP (1.00) | CREBBPEP300TRIM24BRD4BAZ2B | |
| SCHEMBL5362260 | 0.74 | ALDH1A1 (0.51) | — | |
| SCHEMBL30394853 | 0.71 | CREBBP (0.60) | CREBBPEP300TRIM24BRD4BAZ2B | |
| SCHEMBL28629124 | 0.71 | CREBBP (0.60) | CREBBPEP300TRIM24BRD4BAZ2B | |
| SCHEMBL28630407 | 0.70 | CREBBP (0.63) | CREBBPEP300TRIM24BRD4BAZ2B | |
| SCHEMBL4207590 | 0.69 | CREBBP (0.63) | CREBBPEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321640-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-09 | — | — | CN | disclosed |
| CN-109111427-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-02 | — | — | CN | disclosed |
| CN-113321640-A | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2021-08-31 | — | — | CN | disclosed |