Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77925 | 0.89 | ALDH1A1 (0.64) | ALDH1A1HIF1ACYP3A4ALOX15TDP1 | |
| SCHEMBL25837924 | 0.89 | ALDH1A1 (0.64) | ALDH1A1HIF1ACYP3A4ALOX15TDP1 | |
| Hydrochloric Acid SCHEMBL17164230 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HIF1ACYP3A4ALOX15TDP1 | |
| SCHEMBL1020420 | 0.87 | DTYMK (0.46) | ALDH1A1HIF1ACYP3A4ALOX15TDP1 | |
| SCHEMBL28281577 | 0.83 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1CES2 | |
| SCHEMBL670578 | 0.81 | DTYMK (0.46) | ALDH1A1HIF1ACYP3A4ALOX15TDP1 | |
| SCHEMBL195145 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HIF1ACYP3A4ALOX15TDP1 | |
| SCHEMBL1654660 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HIF1ACYP3A4ALOX15TDP1 | |
| SCHEMBL23037543 | 0.78 | CES2 (0.62) | ALDH1A1HIF1ACYP3A4ALOX15TDP1 | |
| SCHEMBL887048 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HIF1ACYP3A4ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226473-A | KIF18A inhibitors | 美国安进公司 | 2021-08-06 | — | — | CN | disclosed |