Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | FPR1 | P21462 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617934 | 0.96 | ALDH1A1 (0.39) | ALDH1A1CNR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28617961 | 0.95 | ALDH1A1 (0.40) | ALDH1A1CNR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28603932 | 0.93 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28919939 | 0.92 | MAPT (0.40) | ALDH1A1CNR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28598799 | 0.91 | IDH1 (0.38) | ALDH1A1CNR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28598858 | 0.91 | IDH1 (0.38) | ALDH1A1CNR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28608487 | 0.91 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28606070 | 0.90 | GRIK1 (0.42) | CNR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28604211 | 0.90 | FPR2 (0.46) | MEN1KMT2AFPR1FPR2NPSR1 | |
| Aza-Flavanone SCHEMBL28608106 | 0.89 | KDR (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |