SCHEMBL2861272

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2865471	0.88	CYP3A4 (0.45)	MAPTAKR1C3AKR1C2CYP2D6CYP2C19
	SCHEMBL2867456	0.86	SLC22A12 (0.42)	MAPTPOLBHTTSLC22A12LMNA
	SCHEMBL15225594	0.86	STS (0.46)	MAPTKDM4EABL1POLBRECQL
	SCHEMBL2862959	0.86	PTGS2 (0.42)	MAPTPOLBCYP2D6CYP2C19HSP90AA1
	SCHEMBL15225836	0.85	MAPT (0.48)	MAPTKDM4EABL1POLBRECQL
	SCHEMBL2871577	0.85	ATM (0.43)	MAPTPOLBHTTALDH1A1LMNA
	SCHEMBL2860047	0.85	PTGS2 (0.42)	AKR1C3AKR1C2HPGDSLC6A2
	SCHEMBL2862917	0.85	HPGD (0.40)	MAPTKDM4EPOLBRECQLCYP2D6
	SCHEMBL2863104	0.85	GAA (0.51)	RECQLCYP2C19CYP3A4HTTGAA
	SCHEMBL2859112	0.85	TSHR (0.51)	MAPTCYP2C19CYP3A4HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.