SCHEMBL2862917

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2867456	0.90	SLC22A12 (0.42)	HPGDL3MBTL1POLBSMN1; SMN2KMT2A
	SCHEMBL2864862	0.87	MAPT (0.42)	ALDH1A1GAAKDM4EHSD17B10POLB
	SCHEMBL2863503	0.86	L3MBTL1 (0.40)	HPGDALDH1A1GAAKDM4EHSD17B10
	SCHEMBL2861272	0.85	MAPT (0.47)	HPGDALDH1A1GAAKDM4EPOLB
	SCHEMBL15225594	0.84	STS (0.46)	HPGDALDH1A1KDM4EHSD17B10POLB
	SCHEMBL2859126	0.84	SRD5A2 (0.44)	BCL2L1
	SCHEMBL2865196	0.83	HSD17B1 (0.38)	ALDH1A1GAAKDM4EPOLBSMN1; SMN2
	SCHEMBL2869188	0.82	TRPA1 (0.35)	HPGDALDH1A1GAAKDM4EHSD17B10
	SCHEMBL2866471	0.82	LCK (0.39)	HPGDALDH1A1GAAKDM4EHSD17B10
	SCHEMBL2859251	0.82	CES2 (0.39)	KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.