Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29483739 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10P2RY10 | |
| SCHEMBL23440856 | 0.87 | LTB4R (0.45) | PPARDLTB4RLTB4R2DHFR | |
| SCHEMBL23440858 | 0.87 | LTB4R (0.45) | PPARDLTB4RLTB4R2DHFR | |
| SCHEMBL21647798 | 0.84 | ADRB2 (0.39) | KDM4EALDH1A1HPGDHSD17B10P2RY10 | |
| SCHEMBL29483750 | 0.84 | ADRB2 (0.39) | KDM4EALDH1A1HPGDHSD17B10P2RY10 | |
| SCHEMBL21647771 | 0.80 | PPARD (0.40) | P2RY10GPR174GPR34PPARDADRB2 | |
| SCHEMBL21647815 | 0.79 | P2RY10 (0.37) | KDM4EALDH1A1HPGDHSD17B10P2RY10 | |
| SCHEMBL21647707 | 0.78 | HTT (0.36) | KDM4EALDH1A1HSD17B10HTT | |
| SCHEMBL31548949 | 0.77 | AURKA (0.41) | ALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL28604318 | 0.77 | AURKA (0.41) | ALDH1A1HPGDADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513011-B | Benzene derivatives | 小野药品工业株式会社 | 2023-06-16 | — | — | CN | disclosed |
| CN-112513011-A | Benzene derivatives | 小野药品工业株式会社 | 2021-03-16 | — | — | CN | disclosed |