Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016003 | 0.83 | ALDH1A1 (0.52) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL8349531 | 0.82 | TDP1 (0.68) | CYP3A4MAPK1ALDH1A1LMNATDP1 | |
| SCHEMBL28514412 | 0.81 | LMNA (0.54) | ALDH1A1LMNATDP1MAPTSMN1; SMN2 | |
| SCHEMBL29016019 | 0.81 | TSHR (0.52) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL29016031 | 0.81 | HCRTR1 (0.52) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL29016068 | 0.80 | TSHR (0.55) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL5709795 | 0.79 | TSHR (0.70) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL1395556 | 0.78 | ALDH1A1 (0.71) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL28188145 | 0.78 | ALDH1A1 (0.71) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL28356625 | 0.77 | LMNA (0.57) | ALDH1A1LMNATDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113230339-A | Enzyme for treating leukemia and preparation method and application thereof | 广东省好杰宏生物医药科技有限公司 | 2021-08-10 | — | — | CN | disclosed |